Urolithin A

Rebuild Your Cellular Power Plants: The Science of Living Better, Longer

Why mitochondria are at the center of longevity, and how a little-known compound called Urolithin A can help keep them youthful.

how urolithin a Rebuilds Your Mitochondria for maximum vitality

As we age, our mitochondria – the powerhouses in every cell – become damaged and dysfunctional, leading to fatigue, reduced resilience, declining endurance, and accelerated biological aging.

Urolithin A is a powerful, research-backed compound that activates mitophagy – your body’s natural process for clearing damaged mitochondria – while stimulating the creation of new, healthy mitochondria, helping restore your natural energy, strength, and cellular health.

Hydrate is safe, supportive, and, according to science, needed by people of every age.

how urolithin a Rebuilds Your Mitochondria for maximum vitality

As we age, our mitochondria – the powerhouses in every cell – become damaged and dysfunctional, leading to fatigue, reduced resilience, declining endurance, and accelerated biological aging.

Hydrate is safe, supportive, and, according to science, needed by people of every age.

Your Body needs urolithin a, but can your gut produce it?

Nature’s most potent longevity foods – pomegranates, walnuts, berries, and chestnuts – contain a remarkable compound called ellagitannin. Through millions of years of evolution, our gut microbiome developed the unique ability to transform this compound into Urolithin A – a powerful molecule that’s essential for maintaining healthy mitochondria and cellular energy.

This biological alchemy is so crucial for our health that our bodies evolved specific mechanisms to produce and use Urolithin A. It’s not just another supplement – it’s a natural compound your body is designed to make.

Most people can't produce Urolithin A-even with a perfect diet

But here’s the modern dilemma: Even when people consistently consume these ellagitannin-rich foods, most can’t produce significant amounts of Urolithin A.

are your gut bugs up to the task?

A 2022 Swiss study found that only 40% of participants had a microbiome that could produce urolithin A ^[4]

Subjects were categorized into three producer groups based on circulating UA glucuronide levels: non-producers, low producers, or high producers.

“Not everyone has a microbiome capable of producing urolithin A, making supplementation…an appealing strategy.”

A: At baseline only 12% subjects had detectable levels of UA glucuronide in circulation with only 2% subjects classified as high producers.

B: Six hours following dietary challenge with PJ approx. 28% subjects had detectable levels of UA glucuronide, with only 4% subjects high producers.

C: One day (T24 hours) after the PJ intake, approx. 40% of subjects had become high converters, whereas 60% still converted poorly or failed to convert the dietary precursors to UA.

Research shows that even after regular consumption of pomegranate juice, 60% of people either produce very little Urolithin A or none at all.

In other words, simply eating these healthy foods with precursors of urolithin A isn’t enough. The reality is that modern life has dramatically altered our gut microbiome.

Widespread factors in today’s world have compromised our microbiome’s ability to produce this vital compound:

Processed foods and low-fiber diets have depleted our beneficial gut bacteria
Frequent antibiotic use has disrupted our microbiome
Chronic stress and environmental toxins have altered our gut health
Metabolic issues and inflammation affect our gut's converting ability
Metabolic syndrome
Lack of consumption of ellagitannin-rich foods such as chestnuts, walnuts, pomegranate, raspberries, strawberries, and pecans
Even with a perfect diet of ellagitannin-rich foods, most people's gut bacteria can't complete this crucial conversion

The solution:

Direct access to urolithin a

Modern science has given us a breakthrough: a way to deliver Urolithin A directly to your cells, bypassing the need for gut conversion entirely.

Now there’s a direct way to get this powerful molecule that activates your body’s natural mitochondrial cleanup system (mitophagy), helping restore your energy, strength, and cellular health – regardless of your gut’s ability to produce it.

This means you can now:

Activate your body's natural mitochondrial cleanup system (mitophagy) even if you don’t have the ideal microbiome
Get a precise, research-backed dose every time
Support the creation of new, healthy mitochondria
Maintain cellular energy and strength into advanced ages
Supporting a key hub of healthy biological aging at the cellular level: your mitochondria

And here’s the bonus: While you’re supporting your cellular health, Urolithin A also provides direct benefits to your gut health [7, 8] – creating a positive cycle of better health from the inside out.

Research-Validated: Urolithin A's Profound Impact on Human Health

Clinical studies reveal that 1-2 capsules of Urolithin A daily triggers profound changes at the cellular level, delivering benefits previously thought impossible:

One to two capsules of Urolithin A provide you with the amounts shown in human studies to:

Activate mitophagy – your body's critical mitochondrial cleanup system that declines with age
Optimize immune health
Significantly increases VO2max - one of the most powerful predictors of longevity
Increases cellular energy production
Dramatically improves muscle strength and endurance in young, middle-aged, and older adults, by halting age-related muscle tissue breakdown

“...the urolithin A group exhibited superior performance enhancements in Maximum Voluntary Isometric Contraction (MVIC) and repetitions to failure (RTF) compared to the placebo group.” ^[11]

*/** Significant difference (p<0.05).

research shows REMARKABLE full-body benefits

improves cardiovascular health:

Benefits Multiple Pathways Implicated in Biological Aging:

Reduce levels of oxidative stress [11, 13]
Decrease inflammatory markers [11]
Possibly protect the brain from age-related atrophy [14]
Amplify the loss of adipose tissue [15], especially belly fat [5]
Possibly support men with prostate cancer [16, 17]
Optimize vascular function [19] and minimize cardiometabolic risk [18]
List ItemAid balanced blood sugar [5]
Deaccelerate biological aging [20] and prolong healthspan [21]

These aren’t just minor improvements – they represent fundamental changes in how your cells function, potentially altering the trajectory of your aging process.

Activate Your Body's Anti-Aging Switch:

The Science of Mitophagy

Every cell in your body relies on a critical renewal process that declines with age. This process – mitophagy – doesn’t just clear out cellular damage. It’s the master switch that determines how well your cells produce energy, how quickly you age, and how resilient you remain over time.

Why Mitophagy Matters

When this process slows down, every system in your body feels it – from your brain to your muscles to your metabolism. This isn’t just aging – it’s your cells losing their ability to regenerate and maintain peak function.

The Urolithin A Discovery: A Scientific Breakthrough

Research reveals that Urolithin A acts as a direct signal to your cells, reactivating this crucial renewal process that naturally declines with age.

“The natural postbiotic Urolithin A has been shown to promote mitophagy, mitochondrial function, and improved muscle function across species in different experimental models and across multiple clinical studies.” ^[3]

Warning Signs Your Cellular Renewal System Needs Support:

Unexplained fatigue that rest doesn't fix
Brain fog and memory issues that impact daily life
Declining strength despite regular activity
Slower recovery from physical or mental challenges
Changes in body composition resistant to diet and exercise
Reduced resilience to stress
Gut dysbiosis

Urolithin a can help you:

Maintain independence and strength throughout life
Support robust cardiovascular and metabolic health
Preserve sharp thinking and mental clarity
Build cellular resilience against aging
Stay active and capable at any age
Support whole-body vitality and function

how can two capsules of urolithin a accomplish so much?

Where the immune system, mitochondria, and microbiome meet [21].

Urolithin A creates a therapeutic cross-talk between your immune system, mitochondria, and microbiome.
How?

Urolithin A works as a diverse biochemical signaler that enhances your body's own immune, mitochondrial, and microbial functions

Learn more about the research behind Urolithin A: [4]

Activates the PINK1/Parkin mitochondrial quality control pathway— optimizes your energy, metabolism, and cell function
Stimulates the Nrf2-ARE signaling pathway that leads to the production of potent internal antioxidants— defends you from brain fog, fatigue, and other signs of aging
Supports the expression of glutathione S-transferases, phase 2 detoxification enzymes— shields your mitochondria from oxidative stress and helps you release harmful toxins
Downregulates pro-inflammatory immune compounds such as C-reactive protein— guards against inflammation in your metabolic, cardiovascular, and musculoskeletal systems
Positively impacts the microbiome [22] and intestinal lining [7, 8]— may increase microbial diversity and intestinal lining health and function

Full Transparency On The Label

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Worldwide Shipping (FREE Shipping within the U.S.)*

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3 Month Supply

Urolithin A

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Worldwide Shipping (FREE Shipping within the U.S.)*

* For international orders: All shipments are shipped Duties, Customs, & Taxes unpaid. Buyer is responsible for delivery fees.

Worldwide Shipping (FREE Shipping within the U.S.)*

* For international orders: All shipments are shipped Duties, Customs, & Taxes unpaid. Buyer is responsible for delivery fees.

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